Adolfo Cotter,MD

Brain-Mind Interface

Dr. Cotter practices Telemedicine in Primary Care. Conducts a competent, highly responsive Telemedicine practice since 2012, treating a variety of medical conditions from simple to very complex. Proficient with electronic medical records using a wide range of software packages and other forms of computing. Dr. Cotter also practiced Medicine doing Home Care, Urgent Care and Hospital Work.

Dr. Cotter has medical licenses in the states of Michigan, Indiana, and telehealth registration in the states of Minnesota and Florida. The links to the states medical boards are: Florida, http://www.flhealthsource.gov/telehealth/ Minnesota, https://mn.gov/boards/medical-practice/ Indiana, https://mylicense.in.gov/everification/ Michigan, https://www.michigan.gov/lara/0,4601,7-154-89334_72600_85566—,00.html

Dr. Adolfo Cotter founded Cognimetrix in 2007, motivated by a tremendous personal interest in the use of brain imaging data in the development of bionic based software to enhance creativity and intelligence.

Throughout his career, Dr. Cotter has performed brain imaging research in academic institutions such as Unversity of Toronto, University of Pennsylvania, and Emory University. He has also conducted brain imaging research for commercial companies such as at Cerebral Diagnostics.

Dr. Cotter has given lectures in Brain Imaging and attended numerous Brain Imaging meetings where he has presented his research projects. He has experience in brain imaging data acquisition and analysis for technologies such as PET, SPECT, MRI, fMRI and EEG. During his brain imaging analysis work, he has done biostatistics using a variety of software programs.

Imaging Neuroinflammation

The benzodiazepine receptor on the mitochondria of activated microglia constitutes a biomarker for neuroinflammation. The  PET radiotracer C11-PK11195 binds to this receptor, making the use of brain images a key diagnostic tool in disease states characterized by neuroinflammation. Alzheimer’s disease (AD) and Multiple Sclerosis (MS) are two such conditions. There has been a debate if there is cell death below the amyloid plaques in AD, but it seems that the main pathology is inflammation. Other Pediatric diseases such as Epilepsy, Cerebral Palsy, Autism and Leukodistrophies also present with inflammation. The measure of inflammation can be used as a biomarker for disease progression and also for response to treatment and drug development. In the case of stroke prevention, imaging inflammation using  PET with FDG can visualize the carotid artery, where it seems that the more inflammation the carotid plaque has, the more it is likely to rupture and develop in an embolic stroke. Thus the measurement of carotid artery inflammation can be used to plan carotid surgery. Here is a good review paper on neuroinflammation:

Kannan S, et al. Positron Emission Tomography Imaging Neuroinflammation, Journal of Child Neurology 24 (9) 1190-1199

Adolfo Cotter, MD

Apr 27/2010

,
Adolfo Cotter, MD's avatar

Posted by:

Adolfo Cotter, MD

Leave a comment