Adolfo Cotter,MD

Brain-Mind Interface

Dr. Cotter practices Telemedicine in Primary Care. Conducts a competent, highly responsive Telemedicine practice since 2012, treating a variety of medical conditions from simple to very complex. Proficient with electronic medical records using a wide range of software packages and other forms of computing. Dr. Cotter also practiced Medicine doing Home Care, Urgent Care and Hospital Work.

Dr. Cotter has medical licenses in the states of Michigan, Indiana, and telehealth registration in the states of Minnesota and Florida. The links to the states medical boards are: Florida, http://www.flhealthsource.gov/telehealth/ Minnesota, https://mn.gov/boards/medical-practice/ Indiana, https://mylicense.in.gov/everification/ Michigan, https://www.michigan.gov/lara/0,4601,7-154-89334_72600_85566—,00.html

Dr. Adolfo Cotter founded Cognimetrix in 2007, motivated by a tremendous personal interest in the use of brain imaging data in the development of bionic based software to enhance creativity and intelligence.

Throughout his career, Dr. Cotter has performed brain imaging research in academic institutions such as Unversity of Toronto, University of Pennsylvania, and Emory University. He has also conducted brain imaging research for commercial companies such as at Cerebral Diagnostics.

Dr. Cotter has given lectures in Brain Imaging and attended numerous Brain Imaging meetings where he has presented his research projects. He has experience in brain imaging data acquisition and analysis for technologies such as PET, SPECT, MRI, fMRI and EEG. During his brain imaging analysis work, he has done biostatistics using a variety of software programs.

Measures of Cortical Brain Thickness

Anatomical MRI measures of cortical brain thickness have been recently evaluated. In normal aging there is a decrease in cortical thickness, which presents an anterior-posterior gradient, being more prominent in Frontal and Parietal than in Temporal and Occipital lobes. There are regional differences between both sexes. In Alzheimer’s disease the reduction in cortical thickness is significantly greater. The sensitivity of AD diagnosis by measurements of cortical thickness is close to 90%, which is higher than with other anatomical measures. In early AD the regions affected are usually medial temporal lobe regions, such as: the hippocampus and entorhinal cortices.

In my opinion, if we combine these anatomical MRI measures with functional ones such as with PET or SPECT, we should obtain higher sensitivity values approaching 100%. This is because anatomical and functional measures are usually synergistic.

The following is a good paper related to this subject:

Thambisetty M, etal., Longitudinal changes in cortical thickness associated with normal aging, NeuroImage, 52 (2010) 1215-1223.

Adolfo Cotter, MD

Aug 16/2010

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